Which one would be the better – Conventional IVF or Mini IVF

Which one would be the better - Conventional IVF or Mini IVF

Infertility is a common problem nowadays for many married couples who want to become parents. It is driven out of this world with the help of the different types of treatments available today. Bringing human life to earth naturally is made possible with the help of these treatments. Like any other treatment option, IVF treatments also have many options.

IVF is one of the best artificial technique by which many infertile couples get the grace of Parenthood.  In fact, in 1978, the first successful IVF pregnancy was the result of a natural cycle—no stimulation medications were used. There are two techniques of IVF treatment. One is Conventional treatment and another is Minimal stimulation Technique.

What is Conventional IVF?

A conventional IVF cycle typically consists of three stages:

  • Preparation
  • Stimulation
  • Retrieval


To maximize the number of eggs being produced, most IVF clinics require patients to undergo a preparation stage before the cycle starts.

Preparation for IVF may involve a combination of:

  • Birth control pills
  • Estrogen pills or patches
  • testosterone topical gel

The primary purpose of the preparation stage is to prevent a lead follicle from developing, thereby increasing the likelihood of follicles growing at a relatively similar rate and thus the remaining follicles get a chance to mature.


The stimulation stage involves daily injections of IVF medication (such as Follistim, Gonal-F, or Menopur) at daily doses of 225 IU or more to stimulate the follicles to grow. However, the administration of high doses of IVF medication to maximize egg production leads to an increased risk of side-effects and other complications.


Prior to retrieval, human chorionic gonadotropin (HCG) is given as a trigger to release the egg and initiate the ovulation process. The use of HCG is meant to mimic what happens naturally when the body is ready to ovulate and the pituitary gland produces a surge of LH: the hormonal surge releases the egg from the follicle wall into the follicle, the follicle ruptures and releases the egg 38-40 hours later.

 What is Mini IVF?

 Twenty years ago, Japan physicians remodeling the IVF treatment by developing Mini IVF and reevaluate the vitality of minimal stimulation protocols following Clomid hyperstimulation method. In this method, Patients are administered Clomid as a daily oral pill in conjunction with a limited number of FSH injections (approx 3-6 injections). It also suppresses the LH surge, which minimizes the risk of premature ovulation. Because fewer follicles are stimulated in a Mini-IVF protocol, egg retrievals are significantly less complicated and can be performed under local anesthesia.

A comparison between these two treatment options is very much essential for you to make a perfect choice. So, here we have entailed some information about those two methods which can help you make the correct decision to choose the right one.

Advantages of Mini IVF over Conventional IVF:

 Mini IVF has a high success rate of pregnancy in comparison to Conventional IVF.

  • Mini IVF has low health risk rates in comparison to Conventional IVF.
  • Mini IVF is less expensive than Conventional IVF
  • In case of Mini IVF, the need of oral medication uptake is comparatively low than in case of conventional IVF.
  • Usage of chemicals in case of Mini IVF is less than in case of Conventional IVF.

With low treatment cost, healthy pregnancy and low physical and mental stress, Mini IVF is one treatment option that can be recommended.

 Frequently Asked Questions:

  1. How does age affect my ability to get pregnant?
  2. The prime productive age for women is between 16 and 28, although one can usually count on good quality eggs until the age of 38. Women belong to the age 39 or more have the lower probability of a successful pregnancy.
  3. Can I still do IVF Even though my cycles are irregular?
  4. Yes, but the course of the treatment will depend on the reasons of irregularity. If you have slow follicular development, your treatment schedule may be adjusted.
  5. Could long flights affect the risk of miscarriage?
  6. There are no scientific or medical studies that we know of that would suggest that this was something to worry about.
  7. How many days will I be on stimulation medication before retrieval?
  8. Most women are usually on medication for 9-13 days.
  9. Do fertility drugs cause cysts?
  10. Sometimes a follicle did not mature in one cycle may evolve into a cyst which appears the following cycle. Cysts do not necessarily mean that you cannot begin another cycle.

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